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| Problem | Medical Rule-Outs | Behavioral Cause | |---------|------------------|------------------| | House soiling (urine) | FLUTD, cystitis, CKD, hyperthyroidism | Litter box aversion, inter-cat conflict, marking | | Aggression | Pain (osteoarthritis, dental), hyperesthesia | Fear, redirected aggression, play aggression | | Over-grooming | Allergies, parasites, pain | Compulsive disorder, psychogenic alopecia |

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Sudden aggression is frequently triggered by pain. Dental disease, spinal injuries, and ear infections can make an animal lash out when touched. | Problem | Medical Rule-Outs | Behavioral Cause

Simultaneously, the field of veterinary psychopharmacology is expanding. Veterinarians now utilize targeted neurotransmitter modulators, including Selective Serotonin Reuptake Inhibitors (SSRIs), Tricyclic Antidepressants (TCAs), and novel alpha-2 adrenoceptor agonists. These medications are not used to sedate or "dope" the animal, but rather to lower their baseline anxiety to a level where cognitive learning and behavior modification can actually take place. Conclusion Sudden aggression is frequently triggered by pain