Steam Cloud frequently overwrites local changes with older cloud data. If your edits disappear when launching the game:
Navigate to the Hypnoot Repentance Save Editor (found on GitHub or modding communities like r/themoddingofisaac). The Binding Of Isaac Repentance Save Editor
This comprehensive guide covers everything you need to know about modifying your Repentance save file safely and effectively. Why Use a Save Editor in Repentance? Steam Cloud frequently overwrites local changes with older
: C:\Program Files (x86)\Steam\userdata\[YourSteamID]\250900\remote\ The Binding Of Isaac Repentance Save Editor